The show, on February 22, at Sidwell Street Methodist Church in Exeter, is a joint concert packed with favourite show-stoppers from the West End and Broadway throughout the years.
The two groups will team up for a one-night-only celebration of the musicals.
The Exeter Male Voice Choir is one of the oldest in Devon, founded in 1900 by a priest at Exeter Cathedral.
The Exe Valley String Quartet is a group of talented young string players who have been successfully performing for the past three years. Tickets at £5 will be available on the door.