Exeter and the surrounding area has been issued a Yellow Alert of snow for the beginning of next week.
The yellow-graded warning, the lowest kind issued by the Met Office, has been put in place for Sunday and Monday.
Forecasters are warning of widespread sleet and snow across the region, with accumulations of up to 5cm possible in some areas.
Temperatures are also expected to plummet this weekend as an influx of cold air passes across the region, while wind speeds could reach up to 50mph.
A chief forecaster at the Exeter-based agency said:
'A spell of sleet and snow is expected, starting on Sunday evening in SW England, and affecting southern England more widely on Sunday night and Monday morning. Snow will be accompanied by a strong easterly wind which will accentuate the very cold feel. Accumulations of 3 - 5 cm could occur quite widely over southern counties, and the public are advised to be aware of this wintry hazard.'
Adding: ‘There is an 80% probability of severe cold weather/icy conditions/heavy snow between 1200 on Saturday and 0800 on Tuesday in parts of England. This weather could increase the health risks to vulnerable patients and disrupt the delivery of services. Please refer to the national Cold Weather Plan and your Trust's emergency plan for appropriate preventive action.
It was announced yesterday that disruptions caused by extreme weather to the region's road and rail network are said to have cost Westcountry businesses £167 million.